Immunohistochemical Characterization of Lymphocyte Subsets in Chronic Adult Periodontitis.

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Cloning, characterization, and antigen specificity of T-lymphocyte subsets extracted from gingival tissue of chronic adult periodontitis patients.

Chronic periodontitis is characterized by dense infiltrations of B and T lymphocytes within the gingival connective tissue. Distinct anaerobic gram-negative bacteria as well as autoimmunity to collagen have been reported to play a role in the etiology and the pathogenesis of this disease. Here we describe the cloning and characterization of CD4+ and CD8+ T lymphocytes isolated from inflamed gin...

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ژورنال

عنوان ژورنال: The Journal of Nihon University School of Dentistry

سال: 1996

ISSN: 1884-2984,0029-0432

DOI: 10.2334/josnusd1959.38.94